Gastric Bypass vs Diet—The Need for Contemporary Comparisons (2024)

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JAMA Surgery

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    Invited Commentary

    July3, 2024

    Leah J.Schoel,MD1; Dana A.Telem,MD, MPH1

    Author Affiliations Article Information

    • 1University of Michigan Department of Surgery, Ann Arbor

    JAMA Surg. Published online July 3, 2024. doi:10.1001/jamasurg.2024.2114

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    • Original Investigation Gastric Bypass vs Diet and Cardiovascular Risk Factors

      CeciliaKarlsson,MD, PhD; Line KristinJohnson,PhD; Peter J.Greasley,PhD; KjetilRetterstøl,MD, PhD; JonatanHedberg,MSc; MartinHall,BSc(Hons); NoeleHawker,BSc(Hons); IdaRobertsen,PhD; JesperHavsol,PhD; Jens KristofferHertel,PhD; RuneSandbu,MD, PhD; EvaSkovlund,PhD; ThomasOlsen,PhD; HegeChristensen,PhD; RasmusJansson-Löfmark,PhD; ShaliniAndersson,PhD; AndersÅsberg,PhD; JøranHjelmesæth,MD, PhD

      JAMA Surgery

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    It is well demonstrated that weight loss surgery, such as Roux-en-Y gastric bypass (RYGB), has long-term benefits for hypertension, type 2 diabetes, and dyslipidemia.1-4 Whether these benefits are secondary to the surgical procedure itself, weight loss alone, or some combination of both, remains unclear.5,6 To answer this question, Karlsson et al7 performed a nonrandomized controlled study at a tertiary care obesity center to determine whether the cardiovascular benefits following RYGB were independent of caloric restriction and weight loss.

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    Schoel LJ, Telem DA. Gastric Bypass vs Diet—The Need for Contemporary Comparisons. JAMA Surg. Published online July 03, 2024. doi:10.1001/jamasurg.2024.2114

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